Search Results - diagnostics+%3e+assay

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Pharmacological EZH2 inhibition enhances cancer cell sensitivity to genotoxic insults through suppressing DNA damage repair

HSC-1535 Pharmacological EZH2 inhibition enhances cancer cell sensitivity to genotoxic insults through suppressing DNA damage repairKexin Xu: Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.Myles Brown: Center for Functional Cancer Epigenetics and Department of Medical Oncology,...

Published: 5/28/2024 | Inventor(s): Kexin Xu, Myles Brown, Chen-Hao Chen, Xiaole Shirley Liu, CPRIT

Keywords(s):

Category(s): Clinical Specialty > Oncology, Clinical Specialty > Radiology, Diagnostics > Assay, Life Sciences Research Tools > Biomarkers

Methods and protein design to increase the efficiency and contrast of photo convertible fluorescent proteins

We disclose two fluorescent protein technologies, which we refer to as “Janus” and “Ignis,” respectively. Bothare green-to-red photoconvertible fluorescent proteins (PC-FPs) of the EosFP family, generated through sitedirectedmutagenesis of the mEos4b protein coding sequence at amino acid positions 41 and 70 (Janus) andpositions...

Published: 5/22/2024 | Inventor(s): Brian Stoveken, James Lechleiter

Keywords(s):

Category(s): Diagnostics > Assay, Life Sciences Research Tools > Proteomics, Life Sciences Research Tools > Reagents

Endocrine Therapy Diagnostic for ER+ Breast Cancer

UT Health San Antonio seeks to partner with a diagnostic products company to develop and commercialize a clinical diagnostic with the potential to determine if a patient with estrogen receptor (ER) positive breast cancer is suitable for treatment with endocrine therapy (e.g., tamoxifen and/or the aromatase inhibitors anastrozole (Arimidex®), letrozole...

Published: 5/28/2024 | Inventor(s): Amy Trauernicht, Thomas Boyer

Keywords(s): Biologics, Drugs

Category(s): Diagnostics > Assay, Clinical Specialty > Oncology, Clinical Specialty > Women's Health