Search Results - chemistry

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Desensitization and Reduction of Chronic Pain

The University of Texas at Dallas presents a novel class of inhibitors, specificity-derived competitive inhibitor oligonucleotides (SPOT-ONs) that bind to poly(A) binding protein (PABP), and the associated inventive strategy to treat pathological pain. Pathological pain plasticity has been shown to take place in nociceptors, sensory neurons which...

Published: 4/26/2019 | Inventor(s):

Keywords(s): Chemistry, Diagnostics, Healthcare, Life Sciences, Molecular Biology, Therapeutics

Category(s): Research Tools

Noninvasive & High-Contrast Imaging of Kidney Function Enabled by Renal Clearable Nanofluorophores

The University of Texas at Dallas is seeking companies interested in commercializing a renal-clearable contrast agent that is the first to enable high-resolution, noninvasive, fluorescent imaging of kidney function. Kidney disease affects more than 10% of adults worldwide and the current technologies used to detect and track the progress of renal complications...

Published: 4/26/2019 | Inventor(s): Jie Zheng, Mengxiao Yu

Keywords(s): Biocompatible, Biomarkers, Chemistry, Diagnostics, Healthcare, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools

Category(s): Biomedical, Imaging

Small Molecule Inhibitor of Forkhead Box Protein C2 (FOXC2): Therapeutic Candidate and Diagnostic Tool for Metastatic Cancers

The transcription factor Forkhead Box Protein C2 (FOXC2) is known to be necessary to initiate and maintain the epithelial-mesenchymal transition (EMT), which has been a hot target for therapeutic intervention against cancers. The overexpression of FOXC2 bestows cancer cells with metastatic and cancer stem cell (CSC)‐like phenotypes, i.e., higher motility,...

Published: 4/26/2019 | Inventor(s): Jiyong Lee, Maria Castaneda

Keywords(s): Assay, Biocompatible, Biomarkers, Chemistry, Drug Delivery, Healthcare, Imaging, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools, Therapeutics

Category(s): Biomedical, Diagnostics

Entering the Fourth Dimension - Manufacturing Responsive Liquid Crystal Elastomer Structures

The University of Texas at Dallas is seeking companies interested in commercializing an innovative method for fabricating Liquid Crystal Elastomer (LCE) structures that undergo reversible actuation in a wide variety of environments. This method uses direct-write additive manufacturing to locally-control the molecular orientation of LCEs, thereby programming...

Published: 4/26/2019 | Inventor(s):

Keywords(s): Chemistry, Devices, Engineering & Physical Sciences, Industrial & Manufacturing, Medical Devices, Microfluidics, Polymers, Processes, Robotics

Category(s): Materials

Portable Electrochemical Impedance System for Universal Molecular Diagnostics

Current methods of producing molecular diagnostic tools have many drawbacks, such as: the high-cost of fabrication, poor biodegradability, limited customizability, or issues with controlled fluid flow. Such problems have limited the ability to create portable detection devices for use in point-of-care settings that use environmentally-safe disposable...

Published: 4/26/2019 | Inventor(s): Shalini Prasad, Anjan Panneer Selvam

Keywords(s): Assay, Biocompatible, Biomarkers, Chemistry, Devices, Electronics, Engineering & Physical Sciences, Healthcare, Life Sciences, Medical, Medical Devices, Microfluidics, Molecular Biology

Category(s): Diagnostics

Novel Solution for Selective Adsorption and Release of Gases Within Porous Materials

The potential for nanoporous materials, such as metal organic frameworks (MOFs), to be used effectively for energy storage and gas capture has been hindered by their relatively weak adsorption of gases. The primary approach for weak adsorption has been to develop metal centers that are more active. Such an approach often leads to complex synthesis procedures...

Published: 4/26/2019 | Inventor(s): Yves Chabal, Kui Tan

Keywords(s): Chemistry, Coatings, Industrial & Manufacturing, Membrane, Nanotechnology

Category(s): Materials

An Environmentally Friendly Solution for Preservation and Increased Nutritional Value of Hay and Forage

Researchers at UT Dallas have developed a preservative solution that can be used in place of current preservatives, such as those that contain propionic acid. Unlike propionic acid, this new preservative solution is much safer and provides additional value to treated feed. Whereas many commercial hay preservatives evaporate over time, this formulation...

Published: 4/26/2019 | Inventor(s): Duck Joo (dj) Yang, Matthew Fiala

Keywords(s): Biocompatible, Chemistry, Industrial & Manufacturing

Category(s): Agriculture

A New Environmentally Friendly Acid for Hydrolysis of Celluloses

Current methods for cellulose hydrolysis have serious setbacks that impede progress in ethanol production from biomass. Researchers at UT Dallas have developed a novel, minimally corrosive acid that can be used in place of the caustic chemicals that are currently used. By using this new organic acid, commercial acid hydrolysis can be undertaken without...

Published: 4/26/2019 | Inventor(s): Duck Joo (dj) Yang, Matthew Fiala

Keywords(s): Agriculture, Biomaterials, Chemistry, Energy, Cleantech & Environmental, Industrial & Manufacturing, Renewable Energy

Category(s): Industrial & Manufacturing

Compatibilized Immiscible Polymer Blends and Molecular Sieve Membranes

Non-Confidential Description: This invention describes novel nanostructured membranes for gas separations, comprising compatibilized, immiscible high performance co-polyimide (PI)/polybenzimidazole (PBI) blends. The compatibilizer used in this invention is a commercially available and inexpensive imidazole-based small molecule (SM). SEM images...

Published: 4/26/2019 | Inventor(s):

Keywords(s): Chemistry, Energy Storage & Battery, Engineering & Physical Sciences, Fuel Cells, Industrial & Manufacturing, Membrane, Polymers

Category(s): Materials

Biscrolling Nanopowders and Carbon Nanotube Sheets into Fibers, Yarns and Textiles

Non-Confidential Description:The technology is the first known method to spin biscrolled fibers/yarns from nanopowder materials using carbon nanotube (CNT) sheets as the host. Nanopowder materials (nanoparticles, nanofibers) are loaded onto the CNT sheets to form bi-layered sheets, which are then scrolled into fibers. A key advantage of this technology...

Published: 4/26/2019 | Inventor(s): Ray Baughman, Shaoli Fang, Marcio Lima, Raquel Robles, Xavier Lepro-Chavez, Mohammad Haque, Anvar Zakhidov, Chihye Lewis Azad, Javier Carretero-Gonzalez, Elizabet Castillo-Martinez, Carter Haines, David Novitski, Mikhail Kozlov

Keywords(s): Chemistry, Coatings, Drug Delivery, Electronics, Energy Storage & Battery, Engineering & Physical Sciences, Healthcare, Processes, Semiconductor, MEMS & Nanotechnology, Textiles

Category(s): Materials, Nanotechnology

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