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Oxytocin to prevent, reduce and reverse Opioid-Induced Respiratory Depression
Opioid-induced respiratory depression is the primary cause of death due to overdose. Opioid antagonism by naloxone (Narcanīĸ), the only FDA-approved drug to treat opioid overdose, causes severe withdrawal related pain and stress in resuscitation patients. Therefore, there is a desperate need for drug targets that counter respiratory depression by opioids...
Published: 5/22/2024
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Inventor(s):
Glenn Toney
,
Allison Brackley
Keywords(s):
Category(s):
Clinical Specialty > Pulmonology
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Clinical Specialty > Pain Management
,
Clinical Specialty > Sleep Disorders
,
Clinical Specialty > Ear, Nose, Throat
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Therapeutics > Analgesics
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Therapeutics > Small Molecule
Antipsychotic Drugs to Reduce the Abuse Liability of Opioids
This invention is a novel use of “atypical” antipsychotic drugs in combination with opioids to reduce the abuse potential of the opioid pain medication. The abuse potential is reduced by inhibiting the stimulation of the reward center in the brain.Background:The global pain market is estimated to reach $21.6 billion USD in 2022 and an estimated...
Published: 5/28/2024
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Inventor(s):
Daniel Lodge
,
Alan Frazer
Keywords(s):
Category(s):
Clinical Specialty > Neurology
,
Clinical Specialty > Pain Management
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Therapeutics > Analgesics